BDNF Essentials® is a clinically researched, comprehensive formula designed to support neurological health and cognitive function. This unique formula leverages ingredients that have been shown to aid in the formation of nerve growth factors, such as brain-derived neurotrophic factor (BDNF). BDNF is essential in supporting neuron health, neuroplasticity (the ability of the brain to rewire and create new connections), and neurogenesis (the growth of new neurons).

Researchers Concluded:

“BDNF Essentials® improved reaction time in measures of working memory, episodic memory, and attention, reduced biomarkers of stress, and [cytokine activity], and improved mood, and sleep.*¹”

Mechanisms of action:

• Supports healthy neuroplasticity & neurogenesis*
• Nurtures healthy cognitive function*
• Promotes balanced cytokine activity*
• Supports cellular membrane health & cortisol levels.*

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CLINICALLY RESEARCHED NEUROPLASTICITY SUPPORT FORMULA*

BDNF Essentials® is a clinically researched, comprehensive formula designed to support neurological health and cognitive function. This unique formula leverages ingredients that have been shown to aid in the formation of nerve growth factors, such as brain-derived neurotrophic factor (BDNF). BDNF is essential in supporting neuron health, neuroplasticity (the ability of the brain to rewire and create new connections), and neurogenesis (the growth of new neurons).

Mechanisms of action:

• Supports healthy neuroplasticity & neurogenesis*
• Nurtures healthy cognitive function*
• Promotes balanced cytokine activity*
• Supports cellular membrane health & cortisol levels.*

What is BDNF?

BDNF is an acronym for brain-derived neurotrophic factor. Brain-derived neurotrophic factor is a protein and a member of the neurotrophin family of growth factors that support and promote neuroplasticity, the ability of the adult brain to reorganize its neural network by forming new connections.

How can you support healthy BDNF levels?

A healthy diet and exercise are key to supporting optimal BNDF formation. However. specific nutrients can provide additional support to the brain's natural ability to generate BDNF. BDNF Essentials® is a comprehensive formula designed to support the brain's formation of nerve growth factors, such as brain-derived neurotrophic factor, which promote neuroplasticity, and neurogenesis.

What is the role of BDNF in the brain?

BDNF Essentials® is a comprehensive BDNF supplement designed to support neurological health. This unique formula leverages ingredients that have been shown to aid in the formation of nerve growth factors, such as brain-derived neurotrophic factor. Brain-derived neurotrophic factor is essential in supporting neuron health, neuroplasticity (the ability of the brain to rewire itself after a traumatic brain injury), and neurogenesis (the growth of new neurons).

In addition to supporting cellular neurological health, this comprehensive formulation is also designed to support healthy cytokine levels within the brain, overall cognitive function, modulation of cortisol levels, and to support healthy brain activity with aging. BDNF Essentials® contains targeted herbs, mushrooms, and nutrients, which have been found to provide brain supporting and protective properties for memory, concentration, and cognitive processing. Research has shown that these BDNF supplement ingredients may promote the healthy production of nerve growth factors to support neuroplasticity.

By providing support for overall cognitive function as well as long-term neuron and cellular health BDNF Essentials® can nurture brain health, neuroplasticity, and mental wellness for patients seeking to promote the health of this vital organ.

Clinical research

Researched Nutritionals® has completed a human clinical research study on BDNF Essentials® which included various clinical and lifestyle measurements to asses the ability of BDNF Essentials® to support healthy cognitive function. The study is currently our for peer review and is expected to be published in early 2023.

Features	Constituents/Actions	Benefits*
NeuroCyto Protect™ Blend	Skullcap Ashwagandha Bacopa Lion’s Mane Bilberry	• Promotes healthy BDNF formation • Supports normal cytokine levels • Nurtures a healthy mood
Cognition Blend	Phosphatidylserine Citicoline	• Support healthy cognitive function • Promote healthy cellular membrane function • Promotes healthy cortisol levels

[1] Lewis D. Erin, Crowley C. David, Hamilton Debby, Guthrie Najla and Evans Malkanthi*, An Open-label Exploratory Study Investigating BDNF Essentials® on Cognition in Healthy Adults with Self-reported Memory Complaints, Current Nutraceuticals 2023; 4 : e171123223619 . https://dx.doi.org/10.2174/0126659786256669230930114915

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Supplement Facts / Dosing

Ingredients

• Choline (as Cytidine Diphosphate Choline Sodium Salt)*** 25 mg
• Sodium (as Cytidine Diphosphate Choline Sodium Salt)*** 5 mg
• NeuroCyto Protect™ Blend | 1175 mg
  • Organic Lion’s Mane Mushroom (Hericium erinaceus) mycelium and fruiting body powder, Skullcap (Scutellaria lateriflora) Herb Powder, Black Rice (Oryza sativa) Seed Extract (25% Anthocyanins), Bacopa (Bacopa monnieri) Herb Powder, Sensoril® Ashwagandha (Withania somnifera) Root and Leaf Extract
• Cognition Blend | 175 mg
  • CDP Choline Sodium Salt, Sharp-PS® Green Phosphatidylserine

Vegetarian

GMO-free

Soy Free

Suggested Use: As a dietary supplement, take 2 capsules twice daily with or without meals, or as directed by your health care professional.

Cautions: If pregnant or nursing, consult your health care professional before use.

***Sodium and Choline are from Cognition Blend

Sensoril® is a registered trademark of Natreon, Inc.

Sharp-PS® is a registered trademark of Enzymotec USA, Inc.

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Frequently Asked Questions

Is the Lion’s Main an extract? No. The Lion’s Main is dried mushroom powder.