***DISCLAIMER***
You are requesting a service from Dr. K, which includes a chart review for eligibility. If approved, the listed item above will be shipped to the specified address on the order. Because this requires a prescription, you must be a registered patient under Dr. K on Push Health. If you have not registered, please click HERE to get started. Unless otherwise approved, new patients must request a 0.25mg dose package or lower of SEMA.
This service request will not be completed until all enrollment steps have been taken. New patients will receive an “Approval Message” through your Push Health account when you are approved for the program and another message once your service has been competed. Returning patients may return and place a new order request when ready and do not need prior approval. Please message us through your Push Health account with any questions before requesting a service.
***SHIPS TO ALL OF MY PATIENTS***
MOTS-C has been marketed as "exercise in a bottle", as many researchers feel that this peptide most closely mimics the effects that exercise has on your body.
TWO DOSING OPTIONS:
Inject 20 units (400mcg) subcutaneously every morning on an empty stomach. Use 5 days on, then 2 days off. One vial will last 5 weeks* and 2 vials will last 10 weeks* with this dosing.
Inject 25 units (500mcg) subcutaneously every morning on an empty stomach. Use 5 days on, then 2 days off. One vial will last 4 weeks* and 2 vials will last 8 weeks* with this dosing. THESE WILL BE THE DIRECTIONS ON YOUR VIAL.
Cycle your injections 10-12 weeks on, then 2-4 weeks off. Repeat as needed.
*It is important to note that the CDC recommends multidose vials such as these to be discarded 4 weeks after mixing to reduce contamination. This is not due to the quality of the medication, but rather to reduce contamination risks. If you use the medication for longer than 4 weeks after mixing, please take extra care when cleaning your vial and your skin to decrease any contamination risks. If you are uncomfortable using the vial for 5 weeks, USE OPTION #2 ABOVE.
WHAT IS MOTS-C PEPTIDE?
MOTS-c is a peptide of 16 amino acids expressed by a mitochondrial gene. Research provides evidence that mitochondria play a key role in signaling and in energy production. Mitochondria are the powerhouses of the cells and produce energy for cells to function.
MOTS-c regulates metabolic functions throughout the body, including turning glucose into usable energy. Preliminary studies show evidence for improved control over blood sugar levels for those with type 2 diabetes and obesity.
Research also shows that skeletal muscle is the major target tissue of MOTS‐c. The skeletal muscle enhances insulin sensitivity and increases glucose uptake in myocytes (muscle cells) by activating the AMPK pathway and at the same time without increasing insulin. It is fair to call MOTS‐c an exercise‐mimetic, meaning it imitates exercise on the body. Exercise also increases muscle glucose uptake without stimulating insulin.
AMPK (AMP‐activated protein kinase), was identified in 1999 as the master switch for metabolism and the central regulator of both glucose and lipid (fat) metabolism. Since then it has been a target for therapeutic intervention against metabolic conditions such as type‐2 diabetes.
WHAT ARE THE POTENTIAL BENEFITS OF MOTS-C PEPTIDE?
MOTS-c promotes fatty acid metabolism in the liver and promotes metabolic flexibility and homeostasis. This helps regulate mitochondrial energy, helps with weight loss, improves exercise capacity, helps prevent osteoporosis, and improves glucose regulation. This also protects against age and diet-dependent insulin resistance and obesity.
HOW CAN MOTS-C PEPTIDE HELP YOUR METABOLISM?
Functional metabolism is fueled by adequate glucose and insulin regulation, optimal mitochondrial functioning, and proper energy usage. Insulin production regulates whether or not the body uses glucose as energy or stores it as fat. Research indicates that the mitochondria are actively involved in metabolic homeostasis at the cellular level. MOTS-c works to reduce insulin resistance, helping the body use carbohydrates more efficiently.
DOES MOTS-C HELP WITH WEIGHT LOSS?
Yes, MOTS-c may aid in weight loss by improving metabolic homeostasis and enhancing physical capacity. It's ability to regulate glucose uptake and lipid metabolism can contribute to more efficient energy utilization within the body while promoting exercise-induced expression of the peptide itself.
SIDE EFFECTS:
MOTS-c is one of those peptides that rarely cause any major side effects. Some people report they have trouble sleeping after the medication, so it is usually best to administer MOTS-C peptide in the morning.
Joint Commission guidelines for proper use of many multi-dose vials include the recommendation to discard the vial 4 weeks after first puncture, even though the Beyond Use Date (BUD) may be longer. These guidelines are generally followed in office and hospital settings, particularly when the vial is used for multiple different patients. However, this same suggestion is made for vials punctured several times a day or only once a week. With certain vial sizes/doses/packages, using all of the medication in the vial without wasting any could result in a patient using the vial for longer than 28 days after first puncture. If you choose to use your vial longer than 28 days after first puncture due to package size or maintenance dosing, you must acknowledge that you understand the Joint Commission recommendations to discard the vial 28 days after first puncture, even if you only puncture the vial once a week. You will be using the vial at your own discretion.
If you are uncomfortable using the vial for 5 weeks, USE OPTION #2.